One-pot synthesis of highly substituted indolinesLIU, Kevin G; LO, Jennifer R; ROBICHAUD, Albert J et al.Tetrahedron (Oxford. Print). 2010, Vol 66, Num 3, issn 0040-4020, 544, 573-577 [6 p.]Article

Radiosynthesis of 123I-labelled benzimidazoles as novel single-photon emission computed tomography tracers for the histamine H3 receptorCHAMPION, Sue; GROSS, Jonathan; ROBICHAUD, Albert J et al.Journal of labelled compounds & radiopharmaceuticals. 2011, Vol 54, Num 9-10, pp 674-677, issn 0362-4803, 4 p.Article

Di-substituted pyridinyl aminohydantoins as potent and highly selective human β-secretase (BACE1) inhibitorsMALAMAS, Michael S; BARNES, Keith; OLLAND, Andrea et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 2, pp 630-639, issn 0968-0896, 10 p.Article

Acylguanidine inhibitors of β-secretase : Optimization of the pyrrole ring substituents extending into the S'₁ substrate binding pocketJENNINGS, Lee D; COLE, Derek C; HARRISON, Boyd L et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 2, pp 767-771, issn 0960-894X, 5 p.Article

Acylguanidine inhibitors of β-secretase : Optimization of the pyrrole ring substituents extending into the S₁ and S₃ substrate binding pocketsCOLE, Derek C; STOCK, Joseph R; GUIXIAN JIN et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 3, pp 1063-1066, issn 0960-894X, 4 p.Article

Discovery and initial optimization of 5,5'-disubstituted aminohydantoins as potent β-secretase (BACE1) inhibitorsNOWAK, Pawel; COLE, Derek C; GUIXAN JIN et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 2, pp 632-635, issn 0960-894X, 4 p.Article

Novel pyrrolyl 2-aminopyridines as potent and selective human β-secretase (BACE1) inhibitorsMALAMAS, Michael S; BARNES, Keith; MANAS, Eric S et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 7, pp 2068-2073, issn 0960-894X, 6 p.Article

1-Sulfonylindazoles as potent and selective 5-HT₆ ligandsLIU, Kevin G; LO, Jennifer R; ROBICHAUD, Albert J et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 9, pp 2413-2415, issn 0960-894X, 3 p.Article

A regiospecific synthesis of a series of 1-sulfonyl azepinoindoles as potent 5-HT₆ ligandsLIU, Kevin G; LO, Jennifer R; ROBICHAUD, Albert J et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 14, pp 3929-3931, issn 0960-894X, 3 p.Article

Identification of 3-sulfonylindazole derivatives as potent and selective 5-HT₆ antagonistsLIU, Kevin G; ROBICHAUD, Albert J; SMITH, Deborah L et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 1, pp 650-662, issn 0968-0896, 13 p.Article

Pyrrolidin-3-yl-N-methylbenzamides as potent histamine 3 receptor antagonistsDAHUI ZHOU; GROSS, Jonathan L; ROBICHAUD, Albert J et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 19, pp 5957-5960, issn 0960-894X, 4 p.Article

3-(Arylsulfonyl)-1-(azacyclyl)-1H-indoles are 5-HT₆ receptor modulatorsBERNOTAS, Ronald C; ANTANE, Schuyler; SHENOY, Rajesh et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 5, pp 1657-1660, issn 0960-894X, 4 p.Article

Novel, highly potent, selective 5-HT_2A/D₂ receptor antagonists as potential atypical antipsychoticsTAEKYU LEE; ROBICHAUD, Albert J; BOYLE, Kristopher E et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 4, pp 767-770, issn 0960-894X, 4 p.Article

N-Aryl pyrrolidinonyl oxadiazoles as potent mGluR5 positive allosteric modulatorsPACKIARAJAN, Mathivanan; MAZZA FERREIRA, Christine G; HONG, Sang-Phyo et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 17, pp 5658-5662, issn 0960-894X, 5 p.Article

Novel 1-aminoethyl-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines are potent 5-HT₆ agonistsBERNOTAS, Ronald C; LENICEK, Steven; PING LI et al.Bioorganic & medicinal chemistry. 2009, Vol 17, Num 14, pp 5153-5163, issn 0968-0896, 11 p.Article

Dual acting norepinephrine reuptake inhibitors and 5-HT_2A receptor antagonists: Identification, synthesis and activity of novel 4-aminoethyl-3-(phenylsulfonyl)-1H-indolesHEFFERNAN, GavinD; COGHLAN, Richard D; COSMI, Scott A et al.Bioorganic & medicinal chemistry. 2009, Vol 17, Num 22, pp 7802-7815, issn 0968-0896, 14 p.Article

Tetrahydrocarbazole-based serotonin reuptake inhibitor/dopamine D₂ partial agonists for the potential treatment of schizophreniaROTELLA, David P; MCFARLANE, Geraldine R; MCCREARY, Andrew et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 19, pp 5552-5555, issn 0960-894X, 4 p.Article

Thiophene substituted acylguanidines as BACE1 inhibitorsFOBARE, William F; SOLVIBILE, William R; GUIXAN JIN et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 19, pp 5353-5356, issn 0960-894X, 4 p.Article

Potent dihydroquinolinone dopamine D₂ partial agonist/serotonin reuptake inhibitors for the treatment of schizophreniaYINFA YAN; PING ZHOU; CARRICK, Tikva et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 9, pp 2983-2986, issn 0960-894X, 4 p.Article

3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3HAVRAN, Lisa M; CHONG, Dan C; KAPOOR, Bhupesh et al.Bioorganic & medicinal chemistry. 2009, Vol 17, Num 22, pp 7755-7768, issn 0968-0896, 14 p.Article

Aminoimidazoles as Potent and Selective Human β-Secretase (BACE1) InhibitorsMALAMAS, Michael S; ERDEI, Jim; OLLAND, Andrea et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 20, pp 6314-6323, issn 0022-2623, 10 p.Article

Novel 1 -(azacyclyl ) -3 -arylsulfonyl -1H -pyrrolo[2,3 -b]pyridines as 5-HT₆ agonists and antagonistsELOKDAH, Hassan; LI, David; MCFARLANE, Geraldine et al.Bioorganic & medicinal chemistry. 2007, Vol 15, Num 18, pp 6208-6226, issn 0968-0896, 19 p.Article

The metabolic disposition of aprepitant, a substance P receptor antagonist, in rats and dogsHUSKEY, Su-Er W; DEAN, Brian J; STRAUSS, John R et al.Drug metabolism and disposition. 2004, Vol 32, Num 2, pp 246-258, issn 0090-9556, 13 p.Article

Azetidinyl oxadiazoles as potent mGluR5 positive allosteric modulatorsPACKIARAJAN, Mathivanan; FERREIRA, Christine G. Mazza; HONG, Sang-Phyo et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 20, pp 6469-6474, issn 0960-894X, 6 p.Article

Benzimidazole- and indole-substituted 1,3'-bipyrrolidine benzamides as histamine H₃ receptor antagonistsCOLE, Derek C; GROSS, Jonathan L; ROBICHAUD, Albert J et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 3, pp 1237-1240, issn 0960-894X, 4 p.Article